The effect of BRAFV600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study

Gabor Liposits; Stine B. Winther; Jesper Ryg; Halla Skuladottir; Sören Möller; Eva Hofsli; Carl Henrik Shah; Laurids Østergaard Poulsen; Åke Berglund; Camilla Qvortrup; Pia Österlund; Bengt Glimelius; Halfdan Sorbye; Per Pfeiffer

doi:10.1016/j.jgo.2023.101632

The effect of BRAF^V600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study

Gabor Liposits, Stine B. Winther, Jesper Ryg, Halla Skuladottir, Sören Möller, Eva Hofsli, Carl Henrik Shah, Laurids Østergaard Poulsen, Åke Berglund, Camilla Qvortrup, Pia Österlund, Bengt Glimelius, Halfdan Sorbye, Per Pfeiffer

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

6 Lataukset (Pure)

Alkuperäiskieli	Englanti
Artikkeli	101632
Julkaisu	JOURNAL OF GERIATRIC ONCOLOGY
Vuosikerta	15
Numero	2
Varhainen verkossa julkaisun päivämäärä	2023
DOI - pysyväislinkit	https://doi.org/10.1016/j.jgo.2023.101632
Tila	Julkaistu - 2024
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Rahoitus

This investigator-initiated study was partly funded by Taiho Pharmaceuticals, Nordic Group, The Danish Cancer Society (grant number: R269-A15859), Academy of Geriatric Cancer Research (AgeCare), The Swedish Cancer Society and the Region of Southern Denmark.

Rahoittajat	Rahoittajan numero
Academy of Geriatric Cancer Research (AgeCare)
Kræftens Bekæmpelse	R269-A15859
Taiho Pharmaceutical
Cancerfonden
Nordic Pharma Group
Region Syddanmark

Julkaisufoorumi-taso

Jufo-taso 0

!!ASJC Scopus subject areas

Oncology
Geriatrics and Gerontology

YK:n kestävän kehityksen tavoitteet

Tämä tuotos edistää seuraavia kestävän kehityksen tavoitteita:

Pääsy asiakirjaan

10.1016/j.jgo.2023.101632Lisenssi: CC BY

1-s2.0-S1879406823002291-mainFinal published version, 797 KBLisenssi: CC BY

https://urn.fi/URN:NBN:fi:tuni-2023112010094Lisenssi: CC BY

Siteeraa tätä

Liposits, G., Winther, S. B., Ryg, J., Skuladottir, H., Möller, S., Hofsli, E., Shah, C. H., Poulsen, L. Ø., Berglund, Å., Qvortrup, C., Österlund, P., Glimelius, B., Sorbye, H., & Pfeiffer, P. (2024). The effect of BRAF^V600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study. JOURNAL OF GERIATRIC ONCOLOGY, 15(2), Artikkeli 101632. https://doi.org/10.1016/j.jgo.2023.101632

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title = "The effect of BRAFV600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study",

keywords = "BRAF, Chemotherapy, Colorectal cancer, Frailty, Older adults, Survival",

author = "Gabor Liposits and Winther, {Stine B.} and Jesper Ryg and Halla Skuladottir and S{\"o}ren M{\"o}ller and Eva Hofsli and Shah, {Carl Henrik} and Poulsen, {Laurids {\O}stergaard} and {\AA}ke Berglund and Camilla Qvortrup and Pia {\"O}sterlund and Bengt Glimelius and Halfdan Sorbye and Per Pfeiffer",

year = "2024",

doi = "10.1016/j.jgo.2023.101632",

language = "English",

volume = "15",

journal = "JOURNAL OF GERIATRIC ONCOLOGY",

issn = "1879-4068",

publisher = "Elsevier Ltd.",

number = "2",

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Liposits, G, Winther, SB, Ryg, J, Skuladottir, H, Möller, S, Hofsli, E, Shah, CH, Poulsen, LØ, Berglund, Å, Qvortrup, C, Österlund, P, Glimelius, B, Sorbye, H & Pfeiffer, P 2024, 'The effect of BRAF^V600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study', JOURNAL OF GERIATRIC ONCOLOGY, Vuosikerta 15, Nro 2, 101632. https://doi.org/10.1016/j.jgo.2023.101632

The effect of BRAF^V600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study. / Liposits, Gabor; Winther, Stine B.; Ryg, Jesper et al.
julkaisussa: JOURNAL OF GERIATRIC ONCOLOGY, Vuosikerta 15, Nro 2, 101632, 2024.

Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - The effect of BRAFV600E mutation on survival and treatment efficacy in vulnerable older patients with metastatic colorectal cancer – A post-hoc exploratory analysis of the randomized NORDIC9-study

AU - Liposits, Gabor

AU - Winther, Stine B.

AU - Ryg, Jesper

AU - Skuladottir, Halla

AU - Möller, Sören

AU - Hofsli, Eva

AU - Shah, Carl Henrik

AU - Poulsen, Laurids Østergaard

AU - Berglund, Åke

AU - Qvortrup, Camilla

AU - Österlund, Pia

AU - Glimelius, Bengt

AU - Sorbye, Halfdan

AU - Pfeiffer, Per

PY - 2024

Y1 - 2024

KW - BRAF

KW - Chemotherapy

KW - Colorectal cancer

KW - Frailty

KW - Older adults

KW - Survival

U2 - 10.1016/j.jgo.2023.101632

DO - 10.1016/j.jgo.2023.101632

M3 - Article

C2 - 37730481

AN - SCOPUS:85171840049

SN - 1879-4068

VL - 15

JO - JOURNAL OF GERIATRIC ONCOLOGY

JF - JOURNAL OF GERIATRIC ONCOLOGY

IS - 2

M1 - 101632

ER -