Transient ordered domains in single-component phospholipid bilayers

Julkaisun otsikon käännös: Transient ordered domains in single-component phospholipid bilayers

T. Murtola, T. Rog, E. Falck, M. Karttunen, I. Vattulainen

    Tutkimustuotos: ArtikkeliScientificvertaisarvioitu

    38 Sitaatiot (Scopus)
    7 Lataukset (Pure)

    Abstrakti

    We report evidence of dense, ordered nanodomains in single-component fluid lipid bilayers. Our atomic-scale molecular dynamics simulations suggest that the area available to a lipid acyl chain exhibits large fluctuations, resulting in denser and sparser domains. The sizes of the dense domains can be up to ∼10  nm, and their lifetimes are of the order of ∼10  ns. In addition, our simulations suggest that domains of lipids with highly ordered acyl chains form predominantly within the dense regions, their sizes ranging from a few chains up to a few nanometers, and with lifetimes between ∼10  ps–10  ns. These observations shed light on the origin of experimentally observed fluctuations, as well as on the mechanisms of phase transitions in lipid membranes.
    Julkaisun otsikon käännösTransient ordered domains in single-component phospholipid bilayers
    AlkuperäiskieliEnglanti
    Sivutpp. 238102
    JulkaisuPhysical Review Letters
    Vuosikerta97
    Numero23, 238102
    DOI - pysyväislinkit
    TilaJulkaistu - 2006
    OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

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