Using AI to Steer Brain Regeneration: The Enhanced Regenerative Medicine Paradigm

Enhanced Regenerative Medicine:Brain regeneration is still far from being possible in a controlled and safe approach, as the biological uncertainties linked to stem cell or bioengineered brain tissue grafting represent a major bottleneck. Here, we describe a novel paradigm based on the use of functional biohybrids as grafts, wherein the integration of bioengineered brain tissue within the diseased host brain is steered by a neuromorphic neuroprosthesis and AI. The symbiotic integration of these biological and artificial (hardware and software) components makes up biohybrid neuronics (neural electronics), establishing the enhanced regenerative medicine paradigm. Furthermore, as biomedical brain implantable devices steered by AI raise psychosocial concerns about human enhancement and mind control, we will address these issues from a philosophical perspective.